Analysis and significance of mRNA in human ejaculated sperm from normozoospermic donors: relationship to sperm motility and capacitation
نویسندگان
چکیده
S.Lambard, I.Galeraud-Denis, G.Martin, R.Levy, A.Chocat and S.Carreau UPRES EA 2608-USC INRA, University of Caen, Department of Genetics and Reproduction, CHRU Clemenceau, Caen 14032 and Laboratory of Reproductive Biology, Hopital Nord, 42055 Saint-Etienne, France To whom correspondence should be addressed at: UPRES EA 2608, USC INRA, Université IRBA, esplanade de la Paix, 14032 Caen cedex, France. E-mail: [email protected]
منابع مشابه
The expression and significance of CATSPER1 in human testis and ejaculated spermatozoa.
AIM To investigate the distribution of cation channel of sperm 1 (CATSPER1) protein and the presence of CATSPER1 mRNA in human testis and ejaculated spermatozoa. The influence of anti-human CATSPER1 antibody upon human sperm motility was used to evaluate the function of human CATSPER1 and to estimate its possible use as a target for immunocontraception. METHODS Human ejaculated sperm from nor...
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متن کاملAnalysis and significance of mRNA in human ejaculated sperm from normozoospermic donors: relationship to sperm motility and capacitation.
The existence of a complex population of mRNA in human sperm is well documented but their role is not yet elucidated. Using discontinuous density gradients, we have isolated high and low motile sperm from the same semen sample. The levels of different transcripts coding for molecules either involved in nuclear condensation (protamines 1 and 2) or in capacitation [endothelial nitric oxide syntha...
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